Oxidative protein-folding systems in plant cells.

ABSTRACT:

Plants are unique among eukaryotes in having evolved organelles

the protein storage vacuole, protein body, and chloroplast. Disulfide transfer pathways that function in the endoplasmic reticulum (ER) and chloroplasts of plants play critical roles in the development of protein storage organelles and the biogenesis of chloroplasts, respectively. Disulfide bond formation requires the cooperative function of disulfide-generating enzymes (e.g., ER oxidoreductase 1), which generate disulfide bonds de novo, and disulfide carrier proteins (e.g., protein disulfide isomerase), which transfer disulfides to substrates by means of thiol-disulfide exchange reactions. Selective molecular communication between disulfide-generating enzymes and disulfide carrier proteins, which reflects the molecula

SUBMITTER: Onda Y 

PROVIDER: S-EPMC3800646 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature