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Reverse orthogonal strategy for oligosaccharide synthesis.


ABSTRACT: Herein, we report the invention of a novel expeditious concept for oligosaccharide synthesis. Unlike the classic orthogonal strategy based on leaving groups, the reverse approach is based on orthogonal protecting groups, herein p-methoxybenzyl and 4-pentenoyl, which allows for efficient oligosaccharide assembly in the reverse direction.

SUBMITTER: Fujikawa K 

PROVIDER: S-EPMC3805137 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature