Autoimmune, neurological, and venous thromboembolic adverse events after immunisation of adolescent girls with quadrivalent human papillomavirus vaccine in Denmark and Sweden: cohort study.

ABSTRACT:

Objective

To assess the risk of serious adverse events after vaccination of adolescent girls with quadrivalent human papillomavirus (qHPV) vaccine.

Design

Register based cohort study.

Setting

Denmark and Sweden, October 2006 to December 2010.

Participants

997,585 girls aged 10-17, among whom 296,826 received a total of 696,420 qHPV vaccine doses.

Main outcome measures

Incident hospital diagnosed autoimmune, neurological, and venous thromboembolic events (53 different outcomes) up to 180 days after each qHPV vaccine dose. Only events with at least five vaccine exposed cases were considered for further assessment. Rate ratios adjusted for age, country, calendar year, and parental country of birth, education, and socioeconomic status were estimated, compari

SUBMITTER: Arnheim-Dahlstrom L 

PROVIDER: S-EPMC3805482 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature