Migraine and white matter hyperintensities: the ARIC MRI study.

ABSTRACT:

Objective

Migraine is associated with white matter hyperintensities (WMH) cross-sectionally, but its effect on WMH progression is uncertain.

Methods

Participants in the Atherosclerosis Risk in Communities cohort study (n = 10,924) completed a standardized headache questionnaire between 1993 and 1995. A subset of participants (n = 1,028) received 2 MRIs 8 to 12 years apart: once at the time of headache ascertainment, and again from 2004 to 2006. WMH were quantified using both a visually graded score (0-9) and semiautomated volumetric analysis. Linear and logistic regression models adjusted for age, sex, and other vascular risk factors were constructed.

Results

Individuals who had migraine without aura were cross-sectionally associated with an 87% greater odds of having

SUBMITTER: Hamedani AG 

PROVIDER: S-EPMC3806921 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature