Differing epidemiological dynamics of influenza B virus lineages in Guangzhou, southern China, 2009-2010.

ABSTRACT: The epidemiological and evolutionary dynamics of the two cocirculating lineages of influenza B virus, Victoria and Yamagata, are poorly understood, especially in tropical or subtropical areas of Southeast Asia. We performed a phylogenetic analysis of the hemagglutinin (HA) and neuraminidase (NA) sequences of influenza B viruses isolated in Guangzhou, a southern Chinese city, during 2009 to 2010 and compared the demographic and clinical features of infected patients. We identified multiple viral introductions of Victoria strains from both Chinese and international sources, which formed two phylogenetically and antigenically distinct clades (Victoria 1 and 2), some of which persisted between seasons. We identified one dominant Yamagata introduction from outside China during 2009. Our phyloge

SUBMITTER: Tan Y 

PROVIDER: S-EPMC3807886 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature