Unknown

Dataset Information

0

Homologous recombination in E3 genes of human adenovirus species D.

ABSTRACT: Genes within the E3 transcription unit of human adenoviruses modulate host immune responses to infection. A comprehensive genomics and bioinformatics analysis of the E3 transcription unit for 38 viruses within human adenovirus species D (HAdV-D) revealed distinct and surprising patterns of homologous recombination. Homologous recombination was identified in open reading frames for E3 CR1?, CR1?, and CR1?, similar to that previously observed with genes encoding the three major structural capsid proteins, the penton base, hexon, and fiber.

SUBMITTER: Singh G 

PROVIDER: S-EPMC3807923 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Homologous recombination in E3 genes of human adenovirus species D.

Singh Gurdeep G   Robinson Christopher M CM   Dehghan Shoaleh S   Jones Morris S MS   Dyer David W DW   Seto Donald D   Chodosh James J  

Journal of virology 20130911 22

Genes within the E3 transcription unit of human adenoviruses modulate host immune responses to infection. A comprehensive genomics and bioinformatics analysis of the E3 transcription unit for 38 viruses within human adenovirus species D (HAdV-D) revealed distinct and surprising patterns of homologous recombination. Homologous recombination was identified in open reading frames for E3 CR1α, CR1β, and CR1γ, similar to that previously observed with genes encoding the three major structural capsid p  ...[more]

Similar Datasets

Unknown Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes.
| S-EPMC6396423 | biostudies-literature
Unknown Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1.
| S-EPMC3518281 | biostudies-literature
Unknown Uncoupling of sexual reproduction from homologous recombination in homozygous Oenothera species.
| S-EPMC3186113 | biostudies-literature
Unknown Herpes ICP8 protein stimulates homologous recombination in human cells.
| S-EPMC6093641 | biostudies-literature
Unknown Genomic Determinants of Homologous Recombination Deficiency across Human Cancers.
| S-EPMC8472123 | biostudies-literature
Unknown Recombination of the epsilon determinant and corneal tropism: Human adenovirus species D types 15, 29, 56, and 69.
| S-EPMC4619159 | biostudies-literature
Unknown Protoplast fusion in Bacillus species produces frequent, unbiased, genome-wide homologous recombination.
| S-EPMC9226520 | biostudies-literature
Unknown Computational analysis of human adenovirus type 22 provides evidence for recombination among species D human adenoviruses in the penton base gene.
| S-EPMC2738150 | biostudies-literature
Unknown New RAD51 Inhibitors to Target Homologous Recombination in Human Cells.
| S-EPMC8235719 | biostudies-literature
Unknown A role for RAD54B in homologous recombination in human cells.
| S-EPMC125815 | biostudies-literature