Damage to the anterior arcuate fasciculus predicts non-fluent speech production in aphasia.

ABSTRACT: Non-fluent aphasia implies a relatively straightforward neurological condition characterized by limited speech output. However, it is an umbrella term for different underlying impairments affecting speech production. Several studies have sought the critical lesion location that gives rise to non-fluent aphasia. The results have been mixed but typically implicate anterior cortical regions such as Broca's area, the left anterior insula, and deep white matter regions. To provide a clearer picture of cortical damage in non-fluent aphasia, the current study examined brain damage that negatively influences speech fluency in patients with aphasia. It controlled for some basic speech and language comprehension factors in order to better isolate the contribution of different mechanisms to fluency,

SUBMITTER: Fridriksson J 

PROVIDER: S-EPMC3808690 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature