Retrospective case studies of the efficacy of caprylic triglyceride in mild-to-moderate Alzheimer's disease.

ABSTRACT: Under normal conditions, the adult human brain is fueled primarily by glucose. A prominent feature of Alzheimer's disease (AD) is region-specific decreases in cerebral glucose metabolism. Ketone bodies are a group of compounds produced from fat stores during periods of low glucose availability that can provide an alternative to glucose for brain metabolism. Consumption of sufficient quantities of caprylic triglyceride (CT) increases plasma concentrations of ketone bodies and may be beneficial in conditions of compromised glucose metabolism, such as AD. The present study describes the use of CT in mild-to-moderate AD in routine clinical practice. Case records from eight patients with extensive monitoring of cognitive function using the Mini-Mental State Examination (MMSE) and who had receiv

SUBMITTER: Maynard SD 

PROVIDER: S-EPMC3810342 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature