Associations of serum uric acid and SLC2A9 variant with depressive and anxiety disorders: a population-based study.

ABSTRACT:

Background

Limited information exists regarding the association between serum uric acid (SUA) and psychiatric disorders. We explored the relationship between SUA and subtypes of major depressive disorder (MDD) and specific anxiety disorders. Additionally, we examined the association of SLC2A9 rs6855911 variant with anxiety disorders.

Methods

We conducted a cross-sectional analysis on 3,716 individuals aged 35-66 years previously selected for the population-based CoLaus survey and who agreed to undergo further psychiatric evaluation. SUA was measured using uricase-PAP method. The French translation of the semi-structured Diagnostic Interview for Genetic Studies was used to establish lifetime and current diagnoses of depression and anxiety disorders according to the DSM-IV cri

SUBMITTER: Lyngdoh T 

PROVIDER: S-EPMC3812204 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature