Reconstructing geographical movements and host species transitions of foot-and-mouth disease virus serotype SAT 2.

ABSTRACT:

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Of the three foot-and-mouth-disease virus SAT serotypes mainly confined to sub-Saharan Africa, SAT 2 is the strain most often recorded in domestic animals and has caused outbreaks in North Africa and the Middle East six times in the last 25 years, with three apparently separate events occurring in 2012. This study updates the picture of SAT 2 phylogenetics by using all available sequences for the VP1 section of the genome available at the time of writing and uses phylogeographic methods to trace the origin of all outbreaks occurring north of the Sahara since 1990 and identify patterns of spread among countries of endemicity. Transitions between different host species are also enumerated. Outbreaks in North Africa appear to have origins in countries immediately south of t

SUBMITTER: Hall MD 

PROVIDER: S-EPMC3812709 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature