Obesity, hyperglycemia and endothelial function in inner city Bronx adolescents: a cross-sectional study.

ABSTRACT:

Background

Along with the rise in obesity, cardiovascular disease (CVD) has become the major cause of death in developed countries. Although overt coronary heart disease rarely manifests during childhood, atherosclerosis can begin by the second decade of life. Therefore, identifying reliable risk markers of early vascular disease in childhood could be important. Alteration in endothelial function (EF) is an early preclinical marker of the atherosclerotic process and can be assessed non-invasively using reactive hyperemia peripheral arterial tonometry (RH-PAT). The purpose of this study was to investigate if obesity in children is associated with lower EF as measured with RH-PAT, and if obese children with impaired glucose regulation have further impairment in RH-PAT measured EF com

SUBMITTER: Agarwal C 

PROVIDER: S-EPMC3816548 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature