Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000 people.

ABSTRACT:

Objective

To determine time to treatment intensification in people with type 2 diabetes treated with one, two, or three oral antidiabetes drugs (OADs) and associated levels of glycemic control.

Research design and methods

This was a retrospective cohort study based on 81,573 people with type 2 diabetes in the U.K. Clinical Practice Research Datalink between January 2004 and December 2006, with follow-up until April 2011.

Results

In people with HbA1c ≥7.0, ≥7.5, or ≥8.0% (≥53, ≥58, or ≥64 mmol/mol), median time from above HbA1c cutoff to intensification with an additional OAD was 2.9, 1.9, or 1.6 years, respectively, for those taking one OAD and >7.2, >7.2, and >6.9 years for those taking two OADs. Median time to intensification with insulin was >7.1, >6.1, or 6.0 year

SUBMITTER: Khunti K 

PROVIDER: S-EPMC3816889 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature