Prandial insulin dosing using the carbohydrate counting technique in hospitalized patients with type 2 diabetes.

ABSTRACT:

Objective

To compare a modified fixed meal dosing strategy to flexible meal dosing in hospitalized patients with type 2 diabetes.

Research design and methods

Patients (N = 126) with refractory hyperglycemia or requiring at least 20 units of insulin per day were randomly assigned to fixed meal dosing (including withholding the dose if less than half of the meal tray was consumed) or flexible meal dosing based upon carbohydrate intake. The inpatient diabetes management team made all treatment adjustments. Outcomes included day 3 mean glucose, 72-h glucose trend analysis, hypoglycemia (<3.9 mmol/L), and inpatient diabetes treatment satisfaction.

Results

The mean glucose on day 3 was 9.5 and 8.8 mmol/L in the fixed and flexible meal groups, respectively (P = 0.26). The fr

SUBMITTER: Dungan KM 

PROVIDER: S-EPMC3816892 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature