Prognostic value of ABO blood group in southern Chinese patients with established nasopharyngeal carcinoma.

ABSTRACT:

Background

ABO blood group is associated with aetiology of nasopharyngeal carcinoma (NPC); however, the effect of it on survival of patients diagnosed with NPC has not been explored.

Methods

We retrospectively analysed two cohorts of southern Chinese patients with WHO histological type III: intensity-modulated radiotherapy (IMRT) cohort, 924 patients; and conventional radiotherapy (CRT) cohort, 1193 patients. Associations of ABO blood group with survival were estimated using Cox regression.

Results

In IMRT cohort, we observed significant associations of blood type A with overall survival (OS) and distant metastasis-free survival (DMFS), compared with type O, after adjusting for prognostic factors. Compared with non-A blood types (B, AB, and O), type A patients had sig

SUBMITTER: Ouyang PY 

PROVIDER: S-EPMC3817319 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature