Topological correlations of structural and functional networks in patients with traumatic brain injury.

ABSTRACT: Despite an increasing amount of specific correlation studies between structural and functional connectivity, there is still a need for combined studies, especially in pathological conditions. Impairments of brain white matter (WM) and diffuse axonal injuries are commonly suspected to be responsible for the disconnection hypothesis in traumatic brain injury (TBI) patients. Moreover, our previous research on TBI patients shows a strong relationship between abnormalities in topological organization of brain networks and behavioral deficits. In this study, we combined task-related functional connectivity (using event-related fMRI) with structural connectivity (derived from fiber tractography using diffusion MRI data) estimates in the same participants (17 adults with TBI and 16 controls), allo

SUBMITTER: Caeyenberghs K 

PROVIDER: S-EPMC3817367 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature