Stereoselective synthesis of the C79-C97 fragment of symbiodinolide.

ABSTRACT: Symbiodinolide is a polyol marine natural product with a molecular weight of 2860. Herein, a streamlined synthesis of the C79-C97 fragment of symbiodinolide is described. In the synthetic route, a spiroacetalization, a Julia-Kocienski olefination, and a Sharpless asymmetric dihydroxylation were utilized as the key transformations.

SUBMITTER: Takamura H 

PROVIDER: S-EPMC3817580 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature