Urine creatinine excretion and clinical outcomes in CKD.

ABSTRACT:

Background and objectives

Twenty-four-hour urine creatinine excretion is a reliable approximation of muscle mass. Whether changes in urine creatinine predict clinical outcomes in persons with CKD is unknown. This work studied the relationship between urine creatinine and patient and renal survival in people with CKD not requiring renal replacement therapy.

Design, setting, participants, & measurements

This longitudinal cohort study included incident stages 3-5 CKD patients referred to the renal clinic at the University Federico II in Naples between January of 1995 and December of 2005. Clinical data and urine creatinine were updated at each visit. Main outcomes were all-cause mortality and kidney failure requiring dialysis.

Results

This study enrolled 525 individuals

SUBMITTER: Di Micco L 

PROVIDER: S-EPMC3817899 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature