Alternative complement pathway activation products in urine and kidneys of patients with ANCA-associated GN.

ABSTRACT:

Background and objectives

Previous study revealed that complement activation products of the alternative pathway could be detected in renal specimens of human ANCA-associated vasculitis. The current study aimed to investigate the clinical and pathologic significance of complement activation products in the urine and kidneys of patients with ANCA-associated vasculitis.

Design, setting, participants, & measurements

Renal biopsy specimens from 29 patients with ANCA-associated vasculitis diagnosed at Peking University First Hospital from January of 2008 to December of 2010 were randomly collected. Urine samples from 27 of 29 patients in active stage and 22 ANCA-associated vasculitis patients in complete remission who were independent of the above-mentioned 29 patients were colle

SUBMITTER: Gou SJ 

PROVIDER: S-EPMC3817906 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature