Albuminuria and cognitive decline in people with diabetes and normal renal function.

ABSTRACT:

Background and objectives

Diabetes mellitus is associated with increased risk of cognitive impairment. This study examines whether microvascular disease, as measured by albuminuria and decline in estimated GFR (eGFR), is associated with cognitive decline during 3.3 years of follow-up in individuals with diabetes with a normal baseline eGFR (approximately 90 ml/min per 1.73 m(2)).

Design, setting, participants, & measurements

Participants were from the Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes study (N=2977; mean age 62.5 ± 5.8 years; recruitment from August 2003 to December 2005, followed through June 2009), which examined the association of intensive versus standard glucose control on cognitive function. Participants underwent three neuropsycholog

SUBMITTER: Barzilay JI 

PROVIDER: S-EPMC3817915 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature