Electrical stimulation for drug-resistant epilepsy: an evidence-based analysis.

ABSTRACT:

Objective

The objective of this analysis was to evaluate the effectiveness of deep brain stimulation (DBS) and vagus nerve stimulation (VNS) for the treatment of drug-resistant epilepsy in adults and children.

Data sources

A literature search was performed using MEDLINE, EMBASE, the Cochrane Library, and the Centre for Reviews and Dissemination database, for studies published from January 2007 until December 2012.

Review methods

Systematic reviews, meta-analyses, randomized controlled trials (RCTs), and observational studies (in the absence of RCTs) of adults or children were included. DBS studies were included if they specified that the anterior nucleus of thalamus was the area of the brain stimulated. Outcomes of interest were seizure frequency, health resource util

SUBMITTER: Chambers A 

PROVIDER: S-EPMC3817921 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature