Resonance Raman spectroscopic evaluation of skin carotenoids as a biomarker of carotenoid status for human studies.

ABSTRACT: Resonance Raman spectroscopy (RRS) is a non-invasive method that has been developed to assess carotenoid status in human tissues including human skin in vivo. Skin carotenoid status has been suggested as a promising biomarker for human studies. This manuscript describes research done relevant to the development of this biomarker, including its reproducibility, validity, feasibility for use in field settings, and factors that affect the biomarker such as diet, smoking, and adiposity. Recent studies have evaluated the response of the biomarker to controlled carotenoid interventions, both supplement-based and dietary [e.g., provision of a high-carotenoid fruit and vegetable (F/V)-enriched diet], demonstrating consistent response to intervention. The totality of evidence supports the use of sk

SUBMITTER: Mayne ST 

PROVIDER: S-EPMC3818359 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature