Electromagnetohydrodynamic modeling of Lorentz effect imaging.

ABSTRACT: Lorentz Effect Imaging (LEI) is an MRI technique that has been proposed for direct imaging of neuronal activity. While promising results have been obtained in phantoms and in the human median nerve in vivo, its contrast mechanism is still not fully understood. In this paper, computational model simulations were used to investigate how electromagnetohydrodynamics (EMHD) may explain the LEI contrast. Three computational models of an electrolyte-filled phantom subject to an applied current dipole, synchronized to oscillating magnetic field gradients of an LEI protocol, were developed to determine the velocity and displacement of water molecules as well as the resulting signal loss in an MR image. The simulated images were compared to images from previous LEI phantom experiments with identical

SUBMITTER: Pourtaheri N 

PROVIDER: S-EPMC3818387 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature