Incidence of intussusception in Singaporean children aged less than 2 years: a hospital-based prospective study.

ABSTRACT:

Background

Continuous surveillance for intussusception (IS) is important for monitoring the safety of second-generation rotavirus vaccines. The present study aimed to assess the incidence of IS in Singaporean children aged < 2 years.

Methods

This was a prospective, hospital-based, multi-center surveillance conducted in seven hospitals - two public hospitals and five private medical centers between May 2002 and June 2010 in Singapore. Diagnosis of IS (definite, probable, possible, suspected) was based on the case definition developed by the Brighton Collaboration. Children < 2 years of age who were diagnosed with IS were enrolled in this study. Incidence of IS was calculated per 100,000 child-year with its 95% confidence interval.

Results

Of the 178 children enrolled,

SUBMITTER: Phua KB 

PROVIDER: S-EPMC3819515 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature