Dissecting organ-specific transcriptomes through RNA-sequencing.

ABSTRACT:

Background

Organ-specific gene expression contains rich information about in vivo biological processes. This kind of information, previously gathered through microarray profiling, has been proven fruitful to the understanding of specific mutants, regulatory events, signaling, and development. With the advent of the next-generation sequencing (NGS) of RNAs, more quantitative and detailed information of gene expressions than previously available can now be collected for each organ or organ developmental stages. The combination of an object-oriented experimental design and an efficient treatment of the high volume information generated through a NGS platform may offer a powerful tool for inferring previously intractable developmental processes.

Results

We collected transcriptom

SUBMITTER: Guan S 

PROVIDER: S-EPMC3819660 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature