Analysis of lipid experiments (ALEX): a software framework for analysis of high-resolution shotgun lipidomics data.

ABSTRACT: Global lipidomics analysis across large sample sizes produces high-content datasets that require dedicated software tools supporting lipid identification and quantification, efficient data management and lipidome visualization. Here we present a novel software-based platform for streamlined data processing, management and visualization of shotgun lipidomics data acquired using high-resolution Orbitrap mass spectrometry. The platform features the ALEX framework designed for automated identification and export of lipid species intensity directly from proprietary mass spectral data files, and an auxiliary workflow using database exploration tools for integration of sample information, computation of lipid abundance and lipidome visualization. A key feature of the platform is the organization

SUBMITTER: Husen P 

PROVIDER: S-EPMC3820610 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature