Lives saved by expanding HIV treatment availability in resource-limited settings: the example of Haiti.

ABSTRACT:

Background

Guidelines recommend antiretroviral therapy (ART) initiation at CD4 <350 cells per microliter for HIV-infected individuals in resource-limited settings. However, funding for treatment expansion remains uncertain. We forecast the mortality impact of ART expansion alternatives in Haiti.

Methods

We used data from Haiti to develop a country-specific model of HIV disease. The model projects the mortality, total number of HIV-infected individuals, and number and coverage (percentage of those eligible) on ART by simulating cohorts of HIV-infected individuals over 10 years. Five ART expansion scenarios, ranging from fully expanded ART (best case) to No New ART (worst case), were assessed.

Results

By 2010, the model predicts 103,500 individuals living with HIV in Ha

SUBMITTER: Kimmel AD 

PROVIDER: S-EPMC3821389 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature