Engineering new protein-protein interactions on the β-propeller fold by yeast cell surface display.

ABSTRACT: REINVENTING THE WHEEL: The β-propeller domain folds like a wheel to provide key protein-protein interactions in the cell. Here we used high-throughput yeast sorting to "invent" β-propellers of new binding specificities with cellular targets.

SUBMITTER: Zhang K 

PROVIDER: S-EPMC3822001 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature