Radiologically isolated syndrome: an uncommon finding at a university clinic in a high-prevalence region for multiple sclerosis.

ABSTRACT:

Objective

The improved availability of MRI in medicine has led to an increase in incidental findings. Unexpected brain MRI findings suggestive of multiple sclerosis (MS) without typical symptoms of MS were recently defined as radiologically isolated syndrome (RIS). The prevalence of RIS is uncertain. The aim of this study was to determine the prevalence of RIS at a university hospital in a region with a high prevalence for MS and describe the long-term prognosis of the identified patients.

Design

Retrospective cohort study conducted in 2012.

Setting

All brain MRI examinations performed at Karolinska University Hospital in Huddinge, Stockholm, Sweden during 2001 were retrospectively screened by a single rater for findings fulfilling the Okuda criteria. The sample year

SUBMITTER: Granberg T 

PROVIDER: S-EPMC3822304 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature