CT-diagnosed emphysema and prognosis of chronic airflow obstruction: a retrospective study.

ABSTRACT:

Objective

CT-diagnosed emphysema is associated with poor prognosis in chronic obstructive pulmonary disease (COPD). Its clinical impacts on prognoses of asthma with chronic airflow obstruction (CAO) are not well known. We sought to compare mortalities and prognostic factors in COPD and asthma with CAO by the presence or absence of CT-diagnosed emphysema.

Design

Retrospective cohort study.

Setting

Referral centre hospital for respiratory disease.

Participants

1272 patients aged over 40 years with CAO (January 2000 to December 2011). CAO was defined as a forced expiratory volume in 1 s/forced vital capacity <0.7 after bronchodilator use throughout the observation period.

Primary and secondary outcome measurements

Overall mortality served as the primary end

SUBMITTER: Kurashima K 

PROVIDER: S-EPMC3822307 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature