Detection of Aortic Wall Inclusion Using Regional Pulse Wave Propagation and Velocity In Silico.

ABSTRACT: Monitoring of the regional stiffening of the arterial wall may prove important in the diagnosis of various vascular pathologies. The pulse wave velocity (PWV) along the aortic wall has been shown to be dependent on the wall stiffness and has played a fundamental role in a range of diagnostic methods. Conventional clinical methods involve a global examination of the pulse traveling between two remote sites, e.g. femoral and carotid arteries, to provide an average PWV estimate. However, the majority of vascular diseases entail regional vascular changes and therefore may not be detected by a global PWV estimate. In this paper, a fluid-structure interaction study of straight-geometry aortas was carried out to examine the effects of regional stiffness changes on PWV. Five homogeneous aortas wit

SUBMITTER: Shahmirzadi D 

PROVIDER: S-EPMC3824606 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature