"Follicular HCG endometrium priming for IVF patients experiencing resisting thin endometrium. A proof of concept study".

ABSTRACT:

Purpose

A thin endometrium is one of the most difficult problems encountered in assisted reproduction every day practice. Whether a daily dose of 150 IU HCG for 7 days concomitant with estrogen administration in estrogen replacement cycles can increase the endometrial thickness and improve pregnancy outcome, was the objective of the current study.

Methods

Seventeen infertile patients with successive implantation failures and resisting thin endometrium, being recipients of fresh donor or frozen embryos were recruited. This was a prospective cohort, proof of concept study, NCT01768247. On day-8 or 9 of the estrogen administration, and continuing 8 mg estrogen per day, subcutaneous injections of 150 IU HCG were initiated daily for 7 days. After a week on HCG priming, (day-14 or

SUBMITTER: Papanikolaou EG 

PROVIDER: S-EPMC3824855 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature