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Oxygenated ylangene-derived sesquiterpenoids from the soft coral Lemnalia philippinensis.


ABSTRACT: Chemical examination of a Taiwanese soft coral Lemnalia philippinensis led to the isolation of three oxygenated ylangene-derived sesquiterpenoids 1-3, including two new metabolites, philippinlins A and B (1 and 2). The structures of these compounds were elucidated on the basis of detailed spectroscopic data. Compound 1 was shown to exhibit cytotoxicity against HepG2, MDA-MB231 and A549 cancer cell lines.

SUBMITTER: Xio YJ 

PROVIDER: S-EPMC3826132 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature

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Oxygenated ylangene-derived sesquiterpenoids from the soft coral Lemnalia philippinensis.

Xio Yun-Jie YJ   Su Jui-Hsin JH   Chen Bo-Wei BW   Tseng Yen-Ju YJ   Wu Yang-Chang YC   Sheu Jyh-Horng JH  

Marine drugs 20130930 10


Chemical examination of a Taiwanese soft coral Lemnalia philippinensis led to the isolation of three oxygenated ylangene-derived sesquiterpenoids 1-3, including two new metabolites, philippinlins A and B (1 and 2). The structures of these compounds were elucidated on the basis of detailed spectroscopic data. Compound 1 was shown to exhibit cytotoxicity against HepG2, MDA-MB231 and A549 cancer cell lines. ...[more]

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