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Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans.

ABSTRACT: We recently demonstrated that the phytotoxin cichorine is produced by Aspergillus nidulans. Through a set of targeted deletions, we have found a cluster of seven genes that are required for its biosynthesis. Two of the deletions yielded molecules that give information about the biosynthesis of this metabolite.

SUBMITTER: Sanchez JF 

PROVIDER: S-EPMC3826659 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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Identification and molecular genetic analysis of the cichorine gene cluster in <i>Aspergillus nidulans.</i>

Sanchez James F JF   Entwistle Ruth R   Corcoran David D   Oakley Berl R BR   Wang Clay C C CC  

MedChemComm 20120801 8

We recently demonstrated that the phytotoxin cichorine is produced by <i>Aspergillus nidulans</i>. Through a set of targeted deletions, we have found a cluster of seven genes that are required for its biosynthesis. Two of the deletions yielded molecules that give information about the biosynthesis of this metabolite. ...[more]

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