Role of intracellular stochasticity in biofilm growth. Insights from population balance modeling.

ABSTRACT: There is increasing recognition that stochasticity involved in gene regulatory processes may help cells enhance the signal or synchronize expression for a group of genes. Thus the validity of the traditional deterministic approach to modeling the foregoing processes cannot be without exception. In this study, we identify a frequently encountered situation, i.e., the biofilm, which has in the past been persistently investigated with intracellular deterministic models in the literature. We show in this paper circumstances in which use of the intracellular deterministic model appears distinctly inappropriate. In Enterococcus faecalis, the horizontal gene transfer of plasmid spreads drug resistance. The induction of conjugation in planktonic and biofilm circumstances is examined here with stoc

SUBMITTER: Shu CC 

PROVIDER: S-EPMC3827321 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature