Genomic testing to determine drug response: measuring preferences of the public and patients using Discrete Choice Experiment (DCE).

ABSTRACT:

Background

The extent to which a genomic test will be used in practice is affected by factors such as ability of the test to correctly predict response to treatment (i.e. sensitivity and specificity of the test), invasiveness of the testing procedure, test cost, and the probability and severity of side effects associated with treatment.

Methods

Using discrete choice experimentation (DCE), we elicited preferences of the public (Sample 1, N = 533 and Sample 2, N = 525) and cancer patients (Sample 3, N = 38) for different attributes of a hypothetical genomic test for guiding cancer treatment. Samples 1 and 3 considered the test/treatment in the context of an aggressive curable cancer (scenario A) while the scenario for sample 2 was based on a non-aggressive incurable cancer (sc

SUBMITTER: Najafzadeh M 

PROVIDER: S-EPMC3827922 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature