Fungal genomes mining to discover novel sterol esterases and lipases as catalysts.

ABSTRACT:

Background

Sterol esterases and lipases are enzymes able to efficiently catalyze synthesis and hydrolysis reactions of both sterol esters and triglycerides and due to their versatility could be widely used in different industrial applications. Lipases with this ability have been reported in the yeast Candida rugosa that secretes several extracellular enzymes with a high level of sequence identity, although different substrate specificity. This versatility has also been found in the sterol esterases from the ascomycetes Ophiostoma piceae and Melanocarpus albomyces.

Results

In this work we present an in silico search of new sterol esterase and lipase sequences from the genomes of environmental fungi. The strategy followed included identification and search of conserved domains

SUBMITTER: Barriuso J 

PROVIDER: S-EPMC3827930 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature