The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis.

ABSTRACT:

Objective

There is substantial uncertainty regarding the prevalence of depression in RA. We conducted a systematic review aiming to describe the prevalence of depression in RA.

Methods

Web of Science, PsycINFO, CINAHL, Embase, Medline and PubMed were searched for cross-sectional studies reporting a prevalence estimate for depression in adult RA patients. Studies were reviewed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and a meta-analysis was performed.

Results

A total of 72 studies, including 13,189 patients, were eligible for inclusion in the review. Forty-three methods of defining depression were reported. Meta-analyses revealed the prevalence of major depressive disorder to be 16.8% (95% CI 10%, 24%

SUBMITTER: Matcham F 

PROVIDER: S-EPMC3828510 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature