Systematic review and meta-analysis of tumor biomarkers in predicting prognosis in esophageal cancer.

ABSTRACT:

Background

Esophageal cancer (EC) is a frequently occurring cancer with poor prognosis despite combined therapeutic strategies. Many biomarkers have been proposed as predictors of adverse events. We sought to assess the prognostic value of biomarkers in predicting the overall survival of esophageal cancer and to help guide personalized cancer treatment to give patients the best chance at remission.

Methods

We conducted a systematic review and meta-analysis of the published literature to summarize evidence for the discriminatory ability of prognostic biomarkers for esophageal cancer. Relevant literature was identified using the PubMed database on April 11, 2012, and conformed to the REMARK criteria. The primary endpoint was overall survival and data were synthesized with haza

SUBMITTER: Chen M 

PROVIDER: S-EPMC3828582 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature