External quality assessment in molecular immunohematology: the INSTAND proficiency test program.

ABSTRACT:

Background

Genotyping for red blood cell (RBC), platelet (PLT), and granulocyte antigens is a new tool for clinical pathology, transfusion medicine services, and blood banks. Proficiency in laboratory tests can be established by external quality assessments (EQAs), which are required for clinical application in many health care systems. There are few EQAs for molecular immunohematology.

Study design and methods

We analyzed the participation and pass rates in an EQA for RBC, PLT, and granulocyte antigens. This EQA was distributed by INSTAND, a large nonprofit provider of proficiency tests, twice per year since Fall 2006 as EQA Number 235 Immunohematology A (molecular diagnostic). The coordinators defined at the outset which alleles are mandatory for detection.

Results

SUBMITTER: Flegel WA 

PROVIDER: S-EPMC3830650 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature