Human papillomavirus infection and increased risk of HIV acquisition. A systematic review and meta-analysis.

ABSTRACT:

Objectives

Human papillomavirus (HPV), one of the commonest sexually transmitted infections, may be a cofactor in HIV acquisition. We systematically reviewed the evidence for an association of HPV infection with HIV acquisition in women, heterosexual men and men who have sex with men (MSM).

Design

: Systematic review and meta-analysis.

Methods

Studies meeting inclusion criteria in Pubmed, Embase and conference abstracts up to 29 July 2011 were identified. Random effects meta-analyses were performed to calculate summary hazard ratios (HR). Publication bias and statistical heterogeneity were evaluated and population attributable fractions (PAFs) calculated.

Results

Eight articles were included, with previously unpublished data from five authors. Seven studies fou

SUBMITTER: Houlihan CF 

PROVIDER: S-EPMC3831022 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature