The osteocalcin gene rs1800247 polymorphism in Kashubian population.
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ABSTRACT:
SUBMITTER: Specjalski K
PROVIDER: S-EPMC3832755 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
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The osteocalcin gene rs1800247 polymorphism in Kashubian population.
Specjalski Krzysztof K Porzezińska Maria M Siemińska Alicja A Słomiński Jan M JM Jassem Ewa E
Rheumatology international 20121212 12
Osteocalcin is the most important noncollagenous protein component of the bone. Polymorphisms of osteocalcin gene were reported to be associated with bone mineral density. However, this relation was only confirmed in some populations. In this study presence of C/T polymorphism in osteocalcin gene (rs1800247) was determined in Kashubian population (northern Poland). The frequencies of variants were CC 9 %, TC 31 %, and TT 60 %, with no significant differences between genders. The genotypes were i ...[more]
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