Clinicopathological and prognostic significance of S100A4 overexpression in colorectal cancer: a meta-analysis.

ABSTRACT:

Background

Accumulated evidence has indicated a correlation between S100A4 expression and colorectal cancer (CRC) progression. However, its prognostic significance for patients with CRC remains inconclusive. To clarify their relationship, a meta-analysis of the relevant published studies was performed.

Method

PubMed, Cochrane Library, and Web of Science databases were electronically searched. All studies evaluating the prognostic value of S100A4 expression in CRC patients regarding survival and a series of clinicopathological parameters were included. The effect of S100A4 expression on the overall survival (OS) and disease-free survival (DFS) were measured by pooled hazard ratios (HRs) and 95% confidence intervals (CIs), while the effect of S100A4 expression on the clinicopa

SUBMITTER: Liu Y 

PROVIDER: S-EPMC3833630 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature