Mortality among Japanese with a history of Kawasaki disease: results at the end of 2009.

ABSTRACT:

Background

The long-term outcomes of Kawasaki disease (KD) are unknown.

Methods

Fifty-two collaborating hospitals collected data on all patients who had received a new definite diagnosis of KD between July 1982 and December 1992. Patients were followed until December 31, 2009 or death. Standardized mortality ratios (SMRs) were calculated based on Japanese vital statistics data.

Results

Of the 6576 patients enrolled, 46 (35 males and 11 females) died (SMR: 1.00; 95% CI: 0.73-1.34). Among persons without cardiac sequelae, SMRs were not high after the acute phase of KD (SMR: 0.65; 95% CI: 0.41-0.96). Among persons with cardiac sequelae, 13 males and 1 female died during the observation period (SMR: 1.86; 95% CI: 1.02-3.13).

Conclusions

In this cohort, the mortalit

SUBMITTER: Nakamura Y 

PROVIDER: S-EPMC3834280 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature