Association between Helicobacter pylori and mortality in the NHANES III study.

ABSTRACT:

Objective

Persistent colonisation by Helicobacter pylori, and especially by cagA-positive strains, has been related to several health outcomes with effects in opposite directions. Thus, it is important to evaluate its influence on total and category-specific mortality.

Design

We conducted prospective cohort analyses in a nationally representative sample of 9895 participants enrolled in the National Health and Nutrition Examination Survey III to assess the association of H pylori status with all-cause and cause-specific mortality. Analyses for the association of H pylori cagA positivity with mortality were conducted in 7384 subjects with data on H pylori cagA status.

Results

In older people (> 40.1 years), H pylori was not associated with all-cause mortality (HR 1.00;

SUBMITTER: Chen Y 

PROVIDER: S-EPMC3834579 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature