Micronutrients supplementation and nutritional status in cognitively impaired elderly persons: a two-month open label pilot study.

ABSTRACT:

Background

Malnutrition is a widespread problem in elderly people and is associated with cognitive decline. However, interventional studies have produced ambiguous results. For this reason, we wanted to determine the effect of micronutrient supplementation on blood and tissue levels and on general nutritional status in persons with mild or moderate cognitive impairment.

Methods

We performed a 2-month, open-label trial, administering a daily micronutrient supplement to 42 memory clinic patients with mild cognitive deficits. Blood levels of antioxidants, zinc, and B vitamins were determined before and after supplementation. In addition, we assessed metabolic markers for B vitamins and intracellular (buccal mucosa cell [BMC]) antioxidant levels. Nutritional status was assessed

SUBMITTER: von Arnim CA 

PROVIDER: S-EPMC3834880 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature