Penile autotransplantation in rats: An animal model.

ABSTRACT:

Context

Penile allotransplantation might be a viable option for patients who need penile reconstruction.

Aims

A successful autotransplantation rat model is the first step toward proceeding for allotransplantation. We herein evaluate autotransplantation following transaction of the rat penis just distal to the urethral bulb.

Settings and design

Experimental animal study.

Materials and methods

Five Sprague-Dawely rats weighing 520 g (SD 19) were used. Utilizing a magnification of 6-40, transection and immediate anastomosis of the tunica albuginea, urethra, dorsal vein and nerves were carried out. Vesicostomy was made to divert urine. The glandular skin was sutured to the perineum and the abdominal wall was closed in layers.

Statistical analysis used

Descri

SUBMITTER: Seyam RM 

PROVIDER: S-EPMC3835983 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature