Improvement in erection hardness and intercourse success with first dose of sildenafil citrate 100 mg.

ABSTRACT:

Purpose

To determine, in men with erectile dysfunction (ED), the extent of improvement in erection hardness and in the rate of successful sexual intercourse (SSI) during the final intercourse attempt using sildenafil 50 mg compared with the subsequent initial attempt after a dose increase to 100 mg.

Patients and methods

This post hoc analysis used data from two randomized, double-blind, placebo-controlled studies of flexible-dose sildenafil for the treatment of men with ED, who were given sildenafil 50 mg or matching placebo, to be taken as needed before sexual intercourse. After 2 weeks, those with no tolerability concerns were titrated up to 100 mg, forming the subgroup of this analysis. The main outcome measures were event log data, including an Erection Hardness Score (E

SUBMITTER: Mulhall JP 

PROVIDER: S-EPMC3836683 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature