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Full genome of influenza A (H7N9) virus derived by direct sequencing without culture.

ABSTRACT: An epidemic caused by influenza A (H7N9) virus was recently reported in China. Deep sequencing revealed the full genome of the virus obtained directly from a patient's sputum without virus culture. The full genome showed substantial sequence heterogeneity and large differences compared with that from embryonated chicken eggs.

SUBMITTER: Ren X

PROVIDER: S-EPMC3837655 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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Full genome of influenza A (H7N9) virus derived by direct sequencing without culture.

Ren Xianwen X Yang Fan F Hu Yongfeng Y Zhang Ting T Liu Liguo L Dong Jie J Sun Lilian L Zhu Yafang Y Xiao Yan Y Li Li L Yang Jian J Wang Jianwei J Jin Qi Q

Emerging infectious diseases 20131101 11

An epidemic caused by influenza A (H7N9) virus was recently reported in China. Deep sequencing revealed the full genome of the virus obtained directly from a patient's sputum without virus culture. The full genome showed substantial sequence heterogeneity and large differences compared with that from embryonated chicken eggs. ...[more]

PMID: 24206919

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