Evidence of vaccine-related reassortment of rotavirus, Brazil, 2008-2010.

ABSTRACT: Analysis of 27 rotavirus strains from vaccinated and unvaccinated children revealed reassortment events in 3 strains: a gene derived from a vaccine; a gene acquired from a circulating strain; and reassortment between circulating strains. Data suggest that the widespread use of this monovalent rotavirus vaccine may introduce vaccine genes into circulating human rotaviruses or vice versa.

SUBMITTER: Rose TL 

PROVIDER: S-EPMC3837663 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature