Bismuth@US-tubes as a Potential Contrast Agent for X-ray Imaging Applications.

ABSTRACT: The encapsulation of bismuth as BiOCl/Bi₂O₃ within ultra-short (ca. 50 nm) single-walled carbon nanocapsules (US-tubes) has been achieved. The Bi@US-tubes have been characterized by high-resolution transmission electron microscopy (HR-TEM), energy-dispersive X-ray spectroscopy (EDS), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. Bi@US-tubes have been used for intracellular labeling of pig bone marrow-derived mesenchymal stem cells (MSCs) to show high X-ray contrast in computed tomography (CT) cellular imaging for the first time. The relatively high contrast is achieved with low bismuth loading (2.66% by weight) within the US-tubes and without compromising cell viability. X-ray CT imaging of Bi@US-tubes-labeled MSCs s

SUBMITTER: Rivera EJ 

PROVIDER: S-EPMC3840030 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature